Inhalon Biopharma has pioneered muco-trapping technology with inhaled immunotherapy for acute respiratory infections

Inhalon’s breakthrough platform for treating acute respiratory infections (ARIs) enables inhaled antibodies to trap viruses and other pathogens in mucus lining the airways, block the infection from spreading within the lung, and rapidly eliminate the germs through natural mucus clearance. This new "muco-trapping" immune function was made possible by key molecular and biophysical insights into antibody-mucin interactions, which allow antibodies to bind to pathogens and trap them in mucus by crosslinking to mucins, the mesh network that makes up mucus. Trapped viruses are carried out of the lung by natural ciliary beating or cough driven expulsion. This unique antibody function is broadly applicable to viruses, bacteria and fungi. Inhalon's muco-trapping technology is protected by four issued patents in the US and Europe and multiple patent applications throughout the world.

Inhalon’s inhaled immunotherapy platform is especially suited for treating ARIs, such as respiratory syncytial virus (RSV), influenza, metapneumovirus (MPV), parainfluenza virus (PIV), adenovirus, coronaviruses, including severe acute respiratory syndrome coronavirus (e.g., SARS-CoV-2) and Middle East respiratory syndrome (MERS). Inhalon’s platform halts the infection immediately, directly clears viruses and other pathogens from infected airways, blocks transmission, requires much less antibody compared to systemic dosing, and allows treatment at the comfort of a patient’s home.​

Learn more about Inhalon here: https://www.inhalon.com/pipeline/.